九州大学 研究者情報
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基本情報 研究活動 教育活動
浅野 周作(あさの しゆうさく) データ更新日:2022.04.28



主な研究テーマ
1 新奇な自律型リアクターシステムの開発
2 固体原料・液体触媒・副生粒子等に関する高度操作手法および反応装置開発
3 有機合成反応や結晶合成プロセスにおける反応工学
キーワード:フローケミストリー, 自動実験, 反応工学, 動的制御
2018.11~2023.11.
従事しているプロジェクト研究
科学研究費助成事業 若手研究 「フローリアクターと自動実験の活用による錯体触媒失活機構の解明」
2020.04~2022.03, 代表者:浅野 周作, 九州大学, 日本学術振興会.
Understanding selective catalyst poisoning and deactivation with automated experiments and machine learning
2020.03~2022.03, 代表者:Nikolay Cherkasov , University of Warwick, The Royal Society (UK).
戦略的イノベーション創造プログラム(SIP)「スマートバイオ産業・農業基盤技術」/アグリバイオ・スマート化学生産システムの開発
2018.11~2023.09, 代表者:林 潤一郎, 九州大学, 内閣府.
研究業績
主要著書
主要原著論文
1. K. Igawa*, S. Asano*, Y. Yoshida, Y. Kawasaki and K. Tomooka, Analysis of Stereochemical Stability of Dynamic Chiral Molecules Using an Automated Microflow Measurement System, JOURNAL OF ORGANIC CHEMISTRY, 10.1021/acs.joc.1c00914, 86, 14, 9651-9657, 2021, 86, 9651-9657, 2021.07, An automated microflow measurement system for the kinetic study of racemization of dynamic chiral molecules was developed. This system facilitated the analysis of fast racemization within several seconds at elevated temperatures owing to its rapid heating ability, high performance for controlling short residence times, and ease of connection to HPLC systems for direct measurement of the enantiomeric purity. A more precise analysis was realized by combination of microflow and common batch measurements over a broad range of temperatures..
2. Jing Xian Wang, Shusaku Asano, Shinji Kudo, Jun Ichiro Hayashi, Deep Delignification of Woody Biomass by Repeated Mild Alkaline Treatments with Pressurized O2, ACS Omega, 10.1021/acsomega.0c03953, 5, 45, 29168-29176, 2020.11, Delignification is essential in effective utilization of carbohydrates of lignocellulosic biomass. Characteristics of the delignification are important for the yield and property of the resulting carbohydrates. Oxidation with O2 of biomass in alkaline water can potentially produce high-purity cellulose at high yield. The present authors chose a Japanese cedar and investigated its oxidative delignification at 90 °C. The delignification selectivity was determined mainly by the chemical structures of lignin and cellulose. Treatment conditions, except for temperature, hardly changed the relationship between delignification rate and cellulose retention. During the treatment, dissolved lignin underwent chemical condensation in the aqueous phase. This "unfavorable"condensation consumed O2-derived active species, slowing down further delignification. Repeated short-time oxidation with renewal of alkaline water suppressed the condensation, enhancing the delignification. Repetition of 2-h treatments four times achieved 96% delignification, which was 8% higher than a single 8-h treatment at 130 °C..
3. Shusaku ASANO, Yu TAKAHASHI, Taisuke MAKI, Yosuke MURANAKA, Nikolay CHERKASOV, Kazuhiro MAE, Contactless mass transfer for intra-droplet extraction, Scientific Reports, 10.1038/s41598-020-64520-4, 10, 7685, 2020.05, This study demonstrates the possibility of “contactless” mass transfer between two aqueous slugs (droplets) separated by an oil slug in Taylor flow inside milli-channels. Separation of the alternating aqueous slugs at the outlet was performed by switching a couple of solenoid valves at branched outlets according to signals obtained by an optical sensor at the branch. Transfer of bromothymol blue (BTB) from acidic to basic aqueous slugs was performed for demonstration. In some cases, aqueous slugs separated by oil, merged catching on each other due to the velocity difference. Interfacial tension which was affected by the solute concentration was responsible for the velocity difference. Position-specific mass transfer activity at the rear end of the aqueous slugs was found on the course of the experiment. A meandering channel decreased the velocity difference and enhanced mass transfer. Almost complete (93%) transfer of BTB was achieved within a short residence time of several minutes under optimized conditions. The presented system opens a way for advanced separation using minimum amounts of the oil phase and allows concentrating the solute by altering relative lengths of the sender and receiver slugs..
4. Asano Shusaku, Choi Cheolyong, Ishiyama Kentaro, Kudo Shinji, Gao Xiangpeng, Hayashi Jun-ichiro, Re-examination of Thermogravimetric Kinetic Analysis of Lignite Char Gasification, Energy & Fuels, 10.1021/acs.energyfuels.9b02946, 33, 11, 10913-10922, 2019.11, [URL].
5. Shusaku Asano, Shota Yatabe, Taisuke Maki, Kazuhiro Mae, Numerical and Experimental Quantification of the Performance of Microreactors for Scaling-up Fast Chemical Reactions, Organic Process Research & Development, 10.1021/acs.oprd.8b00356, 23, 5, 807-817, 2019.05, [URL], Microreactors have been utilized for controlling fast chemical reactions. However, the scale-up strategy for fast reactions is not established enough due to the difficulty in quantifying the effect of the reactor size on the mixing performance, heat removal, and observable reaction rate. We present a chart for analyzing the effect of the mixing rate on the observable kinetic constant and a chart for estimating the temperature increase in the reactor. By using these charts, the validity of the rate analysis and the maximum reactor diameter, which control the reaction temperature, were determined. Commercial computational fluid dynamics (CFD) software was employed to solve the partial differential equations and to build the charts, and experiments were conducted to validate the results. We demonstrated the concept by using the ultrafast organolithium reaction in milliseconds. The product throughput was increased eight times with a reactor diameter that was twice as wide as the original reactor..
6. Shusaku Asano, Taisuke Maki, Victor Sebastian , Klavs F. Jensen, Kazuhiro Mae, Revealing the Formation Mechanism of Alloyed Pd–Ru Nanoparticles: A Conversion Measurement Approach Utilizing a Microflow Reactor, Langmuir, 10.1021/acs.langmuir.8b03516, 35, 6, 2236-2243, 2019.01, [URL], The synthesis of alloyed nanoparticles has been studied extensively; however, the formation mechanisms involved remain unclear. Here, we reveal the detailed formation mechanism of alloyed nano- particles in a Pd−Ru system, using a semibatch polyol method in which the simultaneous rapid reduction of both precursors was assumed to be the critical mechanism. We employed a microflow reactor to realize rapid heating and cooling. A significant difference in the reaction rate between the two precursors was observed. Pd was reduced within seconds, but the reduction of Ru was 2 orders of magnitude slower than that of Pd and was not as rapid as previously assumed. Further investigation of the semibatch method was performed to trace changes in the particle sizes and composition. Through quantitative and multilateral evidence, we concluded that the formation of low-crystallinity seeds, followed by solid-state diffusion, is the governing mechanism for the formation of alloyed Pd−Ru nanoparticles.
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7. Syusaku Asano, S. Yamada, T. Maki, Y. Muranaka, K. Mae, Design protocol of microjet mixers for achieving desirable mixing times with arbitrary flow rate ratios, Reaction Chemistry and Engineering, 10.1039/c7re00051k, 2, 6, 830-841, 2017.12, [URL].
8. Syusaku Asano, Taisuke Maki, Ryutaro Nakayama, Ryuji Utsunomiya, Yosuke Muranaka, Toshiharu Kuboyama, Kazuhiro Mae, Precise analysis and control of polymerization kinetics using a micro flow reactor, Chemical Engineering and Processing - Process Intensification, 10.1016/j.cep.2017.05.016, 119, 73-80, 2017.01, [URL].
9. Syusaku Asano, Taisuke Maki, Kazuhiro Mae, Evaluation of mixing profiles for a new micromixer design strategy, AIChE Journal, 10.1002/aic.15082, 62, 4, 1154-1161, 2016.04, [URL].
主要総説, 論評, 解説, 書評, 報告書等
主要学会発表等
1. ASANO Shusaku, HIRAI Ryota, MAKI Taisuke, MAE Kazuhiro, Relationship between product composition and kinetics of precursor reduction during polyol synthesis of bimetallic nanoparticles, APCChE 2019 Congress, 2019.09.
2. ASANO Shusaku, INOUE Shogo, MAKI Taisuke, MAE Kazuhiro, Effect of mixing behaviors on fine particle synthesis in a flow microreactor, APCChE 2019 Congress, 2019.09.
学会活動
所属学会名
American Chemical Society
近畿化学協会
化学工学会
学術論文等の審査
年度 外国語雑誌査読論文数 日本語雑誌査読論文数 国際会議録査読論文数 国内会議録査読論文数 合計
2021年度
2020年度      
2019年度      
研究資金
科学研究費補助金の採択状況(文部科学省、日本学術振興会)
2021年度~2024年度, 基盤研究(A), 分担, バイオマス逐次炭化による基礎化学品と製鉄用コークスの製造.
2022年度~2023年度, 若手研究, 代表, 可逆的触媒毒の選択的作用機構の解明と最適触媒毒構造導出法の構築.
2021年度~2023年度, 学術変革領域研究(B), 代表, フロー反応シミュレーションによる低エントロピー反応空間の基礎理論と設計論の構築.
2015年度~2017年度, 特別研究員奨励費, 代表, マイクロリアクター設計手法の構築と精密合成反応プロセスへの応用.
2020年度~2021年度, 若手研究, 代表, フローリアクターと自動実験の活用による錯体触媒失活機構の解明.
2020年度~2024年度, 基盤研究(S), 分担, キラル分子を光学活性体として得る革新的手法DYASINの開発.
2020年度~2022年度, 挑戦的研究(開拓), 分担, カーボンニュートラル製鉄・化学を実現する五元素サイクル.
寄附金の受入状況
2019年度, 生産科学研究奨励会, 若手研究者研究助成.

九大関連コンテンツ

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