||Anil Khar,Sho Hirata,Mostafa Abdelrahman,Masayoshi Shigyo,Hira Singh, Garlic-Breeding and Genomic Approaches for Climate Resilient Sustenance. GENOMIC DESIGNING FOR CLIMATE SMART CROPS., Springer, Cham, https://doi.org/10.1007/978-3-319-97415-6_8, 2020.03, Garlic (Allium sativum L.) has a long history of cultivation by asexual propagation. Due to its asexual nature, improvement of garlic has been limited as compared to onion. With the impending climate change, it is predicted that like all other crops, garlic cultivation will also suffer the consequences. Ninety percent of garlic is grown in Asia and increase in temperature will expose garlic to various biotic and abiotic stresses. To evolve against these stresses, quality improvement of garlic to withstand these stresses is of principal concern. Research work on creation of genetic diversity, collection of genetic resources, interspecific hybridization, and manipulation of flowering is needed through conventional techniques. Biotechnological approaches for garlic improvement through genetic transformation, marker-assisted selection, genomics-aided breeding, and other novel technologies may help in achieving higher yields under climate change scenarios. In this chapter, we have discussed various approaches and what has been done in these areas in different parts of the world to address the loss in crop yield which is likely to be caused by the biotic and abiotic stresses in the future..