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List of Presentations
Asako Murata Last modified date：2023.05.31

Associate Professor / Department of Advanced Materials Science and Engineering / Faculty of Engineering Sciences


Presentations
1. 配座を制限したナフチリジン誘導体の合成と核酸への結合評価.
2. 核酸に結合する小分子のエンタルピー駆動型分子設計と合成.
3. 小分子誘起型–1リボソームフレームシフトによる遺伝子発現制御システムの開発.
4. 小分子化合物によるマイクロRNA生成阻害の速度論的解析.
5. 小分子によるマイクロRNA前駆体のプロセシング阻害.
6. 小分子によるリボソームフレームシフトの制御.
7. 小分子による–1リボソーマルフレームシフト誘起とタンパク質の輸送・局在制御への応用.
8. 小分子によるmiR-29a成熟過程の阻害.
9. 小分子によるRNAシュードノット構造の形成とフレームシフトの制御への応用.
10. 小分子とトリヌクレオチドリピートDNAおよびRNAとのSPRによる結合評価.
11. 小分子で誘起されたRNAシュードノット構造によるフレームシフト機構の制御.
12. 小分子で制御するリボソームフレームシフトを用いた遺伝子発現制御.
13. 大規模化合物ライブラリーのスクリーニングによる，RNA結合性化合物の探索.
14. 中性条件下切り出し可能なリンカーを用いたセリン骨格を有する新規核酸類縁ポリエステルの固相合成.
15. 中性条件下切り出し可能なリンカーを用いたセリン骨格を有する新規核酸類縁ポリエステルの固相合成.
16. 中性条件下切り出し可能なリンカーを用いたセリン骨格を有する新規核酸類縁ポリエステルの固相合成.
17. マイクロＲＮＡ-低分子化合物の相互作用を検出するアッセイ法の開発.
18. マイクロRNA前駆体結合分子の探索.
19. セリン骨格を有する新規核酸類縁ポリエステルの固相合成.
20. セリン骨格を有する新規核酸類縁ポリエステルの固相合成.
21. キサントン誘導体のRNA 小分子間相互作用を検出するディスプレイスメントアッセイ指示薬としての評価.
22. "[Muhammad Nurrohman Sidiq,Asako Murata,Kazuhiko Nakatani]", qPCR-based Screening Methods for Small Molecules that Modulate Dicer-mediated pre-miR-182/31/30d Processing, 第48回国際核酸化学シンポジウム.
23. "[Qingwen Chen,Yasuyuki Matsushita,Asako Murata,Takeshi Yamada,Ayako Sugai,Kazuhiko Nakatani]", Using machine learning to classify and extract features of small-molecule libraries targeting DNA and RNA, The 2021 International Chemical Congress of Pacific Basin Societies (Pacifichem2021).
24. "[Saki Matsumoto,Changfeng Hong,Asako Murata,Kazuhiko Nakatani]", Translational regulation by ligand-inducible formation of RNA pseudoknot, The 18th Annual Meeting of the RNA Society (RNA2013).
25. "[Saki Matsumoto,Changfeng Hong,Asako Murata,Kazuhiko Nakatani]", Translation regulation of gene expression by small molecule-induced pseudoknot formation, 第39回国際核酸化学シンポジウム.
26. "[Qingwen Chen,Takeshi Yamada,Asako Murata,Kazuhiko Nakatani]", The binding motif of naphthyridine-azaquinolone dimer (NAD) in CAG-repeat RNA, 日本化学会第102春季年会.
27. "[Asako Murata,Ayako Sugai,Takeo Fukuzumi,Shiori Umemoto,Chikara Dohno,Kazuhiko Nakatani]", Targeting secondary structures of pre-miRNA by small molecules : Development of potential inhibitors of pre-miRNA processing, The 18th Annual Meeting of the RNA Society (RNA2013).
28. "[Asako Murata,Saki Matsumoto,Neva Caliskan,Marina V. Rodnina,Kazuhiko Nakatani]", Synthetic small molecule-stabilized RNA pseudoknot as an activator for –1 ribosomal frameshifting, 第45回国際核酸化学シンポジウム.
29. "[Yue Di,Takahiro Otabe,Jinxing Li,Asako Murata,Kazuhiko Nakatani]", Synthesis of the restrained naphthyridine dimer and the exploration for binding RNA by in vitro selection, 第40回国際核酸化学シンポジウム.
30. Synthesis of circular mismatch binding ligands and their binding properties to DNA and RNA.
31. "[Takeo Fukuzumi,Asako Murata,Yasue Harada,Kazuhiko Nakatani]", Synthesis of Small Molecule Library for pre-miRNA Secondary Structures, The 17th Annual Meeting of the RNA Society (RNA 2012).
32. "[Takeo Fukuzumi,Asako Murata,Yasue Harada,Kazuhiko Nakatani]", Synthesis of Small Molecule Library for pre-miRNA Secondary Structures, The 12th International Kyoto Conference on New Aspects of Organic Chemistry (IKCOC-12).
33. "[Takahiro Otabe,Asako Murata,Fumie Takei,Kazuhiko Nakatani]", Synthesis of RNA bulge binding small molecule and application to inhibitor of Dicer cleavage reaction, The 1st Osaka University - EPFL International Symposium.
34. "[Qingwen Chen,Takeshi Yamada,Asako Murata,Kazuhiko Nakatani]", Synthesis and the properties of NA Dimer, 日本化学会第100春季年会.
35. "[Qingwen Chen,Takeshi Yamada,Asako Murata,Kazuhiko Nakatani]", Synthesis and the properties of naphthyridine-azaquinolone dimer (NAD) tatgeting CAG-repeat RNA, 日本化学会第101春季年会.
36. "[Haruo Aikawa,Takeo Fukuzumi,Asako Murata,Yasue Harada,Kazuhiko Nakatani]", Synthesis and Evaluation of 8-substituted Adenine Derivatives as RNA Binding Molecules, The 19th Annual Meeting of the RNA Society (RNA2014 ).
37. "[Akihiro Sakata,Jinxing Li,Hanping He,Li-ping Bai,Asako Murata,Chikara Dohno,Satoshi Obika,and Kazuhiko Nakatani]", Synthesis and Binding Property of Naphthyridine-Azaquinolone Derivatives Targeting (CAG)n Repeat RNA, 第42回国際核酸化学シンポジウム.
38. "[Takahiro Otabe,Asako Murata,Fumie Takei,Kazuhiko Nakatani]", Suppression of miR-29a maturation by ligand binding, The 18th Annual Meeting of the RNA Society (RNA2013).
39. "[Takahiro Otabe,Jinxin Li,Asako Murata,Kazuhiko Nakatani]", Suppression of miR-29a maturation by synthetic ligand, 第41回国際核酸化学シンポジウム.
40. "[Sanjukta Mukherjee,Leszek Blaszczyk,Wojciech Rypniewski,Christoph Falschlunger,Ronald Micura,Asako Murata,Chikara Dohno,Kazuhiko Nakatani,Agnieszka Kiliszek]", Structural insights into synthetic ligands targeting A-A pairs in disease-related CAG RNA repeats, The 24th Annual Meeting of the RNA Society (RNA 2019).
41. "[Asako Murata,Shinichi Sato,Yoshinori Kawazoe,Motonari Uesugi]", Small molecule-based FRET probes for specific RNA targets, The 5th Japan-Korea Chemical Biology Symposium.
42. "[Yuki Mori,Yue Di,Ayako Sugai,Asako Murata,Kazuhiko Nakatani]", Small molecule-Loop Interaction that interferes the maturation on process of pre-miRNA by Dicer, 第42回国際核酸化学シンポジウム.
43. "[Muhammad Nurrohman Sidiq,Asako Murata,Kazuhiko Nakatani]", Screening of small molecules that interfere dicer-mediated processing of pre-miR-182/31/30d, 日本ケミカルバイオロジー学会 第15回年会.
44. SPRを用いたin vitro selectionによるRND(the restrained naphthyridine dimer)結合性RNAアプタマーの探索.
45. "[Yuki Mori,Yue Di,Ayako Sugai,Asako Murata,Kazuhiko Nakatani]", SPR-based in vitro selection of pre-miRNA loop mutant molecules that bind to the restrained naphthyridine dimer, The 2015 International Chemical Congress of Pacific Basin Societies (Pacifichem2015).
46. SARS-CoV-2フレームシフトシグナルを標的とする低分子化合物の表面プラズモン共鳴(SPR)アッセイによるスクリーニング.
47. "[Saki Matsumoto,Asako Murata,Changfeng Hong,Kazuhiko Nakatani]", Regulation of –1ribosomal frameshifting by ligand-induced RNA pseudoknot formation, XXI International Round Table on Nucleosides, Nucleotides and Nucleic acids (IRT2014).
48. "[Saki Matsumoto,Asako Murata,Changfeng Hong,Kazuhiko Nakatani]", Regulation of gene expression by ligand-inducible –1 ribosomal frameshifting, The 20th Annual Meeting of the RNA Society (RNA2015).
49. "[Saki Matsumoto,Asako Murata,Changfeng Hong,Kazuhiko Nakatani]", Regulation of gene expression by ligand-inducible –1 ribosomal frameshifting, ECBS & ICBS joint meeting 2015.
50. "[Lu Ni,Takeshi Yamada,Asako Murata,Kazuhiko Nakatani]", Regulation of circular RNA biogenesis via RNA binding small molecule, 日本化学会第101春季年会.
51. "[Lu Ni,Takeshi Yamada,Asako Murata,Kazuhiko Nakatani]", Regulation of circular RNA biogenesis via nucleic acid binding small molecule in cells, 第48回国際核酸化学シンポジウム.
52. "[Lu Ni,Takeshi Yamada,Asako Murata,Kazuhiko Nakatani]", Regulation of circular RNA biogenesis using nucleic acid binding small molecule in cellular environment, The 2021 International Chemical Congress of Pacific Basin Societies (Pacifichem2021).
53. "[Takeshi Yamada,Lu Ni,Asako Murata,Kazuhiko Nakatani]", Regulation of circRNA expression in cell via RNA binding small molecule, IS3NA-IRT virtual symposium 2021.
54. "[Saki Matsumoto,Asako Murata,Changfeng Hong,Kazuhiko Nakatani]", Regulation of Ribosomal Frameshifting by Ligand-inducible Formation of RNA Pseudoknot, The 17th SANKEN international Symposium 2013/ The 12th SANKEN Nanotechnology Symposium.
55. Rational design of CUG repeat binging molecule targeting Myotonic Dystrophy type 1.
56. RNA結合性小分子の創成を指向したエンタルピー駆動型分子の設計と合成.
57. RNA結合性化合物を用いたマイクロRNA前駆体プロセシングの調節.
58. RNAバルジ結合性小分子の合成とDicer切断反応の阻害剤としての利用.
59. RNAを標的とする小分子ライブラリーの合成.
60. RNAを標的とする創薬を指向した小分子ライブラリーの合成.
61. RNAを標的とする低分子の探索と応用.
62. RNAの構造・機能を制御する小分子化合物の開発.
63. RNAに結合する小分子のエントロピー駆動型分子設計と合成.
64. RNAに結合する小分子のエンタルピー駆動型分子設計と合成.
65. "[Jun Matsumoto,Jinxing Li,Asako Murata,Chikara Dohno,Kazuhiko Nakatani]", Novel isoquinoline derivatives that inhibit MBNL1-CUG repeat interaction in Myotonic Dystrophy type1, 第44回国際核酸化学シンポジウム.
66. "[Luyan Zhang,Asako Murata,Kazuhiko Nakatani]", Modulation of cytosine deamination catalyzed by Deoxycytidine Deaminase APOBEC by binding of small molecule to DNA, 第48回国際核酸化学シンポジウム.
67. "[Luyan Zhang,Asako Murata,Kazuhiko Nakatani]", Modulation of APOBEC-catalyzed cytosine deamination by a small molecule binding to DNA, 日本化学会第102春季年会.
68. "[Qingwen Chen,Yasuyuki Matsushita,Asako Murata,Takeshi Yamada,Ayako Sugai,Kazuhiko Nakatani]", Machine learning-based classification in small molecules targeting CAG-repeat DNA, FIBER日本核酸化学学会若手フォーラム2021.
69. Ligand-inducible –1 ribosomal frameshifting in the cells.
70. "[Asako Murata,Takahiro Otabe,Konami Nagano,Gota Kawai,Ayako Sugai,Kazuhiko Nakatani]", Kinetic analysis of the inhibitory effect of BzDANP on Dicer cleavage of pre-miR-136, The Commemorative International Symposium of the Japan Society of Nucleic Acids Chemistry (CISNAC 2019).
71. "[Asako Murata,Ayako Sugai,Izumi Kohyama,Chikara Dohno,Kazuhiko Nakatani]", Inhibition of hairpin RNA processing by Dicer using RNA-binding small molecules, Technologies for Medical Diagonosis and Therapy (G4 Meeting).
72. "[Yuki Mori,Yue Di,Ayako Sugai,Takahiro Otabe,Jinxin Li,Haruo Aikawa,Asako Murata,Kazuhiko Nakatani]", In vitro selection of pre-miR-29a loop mutant library against the restrained naphthyridine dimer, 第41回国際核酸化学シンポジウム.
73. "[Asako Murata,Yuki Mori,Yue Di,Ayako Sugai,Kazuhiko Nakatani]", In vitro selection of pre-miRNA loop mutant molecules that bind to the restrained naphthyridine dimer, The 20th Annual Meeting of the RNA Society (RNA2015).
74. "[Sanjukta Mukherjee,Asako Murata,Kazuhiko Nakatani]", In vitro selection of pre-miR-29a loop mutant against the cyclic mismatch binding ligand (CMBL), 第43回国際核酸化学シンポジウム.
75. "[Hiyori Fujii,Asako Murata,Kazuhiko Nakatani]", Identification of small molecules that can bind to the SARS-CoV-2 frameshifting signal by SPR-based screening of chemical libraries, 第48回国際核酸化学シンポジウム.
76. "[Asako Murata,Yasue Harada,Takeo Fukuzumi,Shiori Umemoto,Seongwang Im,Masaki Hagihara,Kazuhiko Nakatani]", High-throughput Screening of Chemical Libraries for the Discovery of RNA-binding Compounds, The 17th Annual Meeting of the RNA Society (RNA 2012).
77. G-Gミスマッチ結合性リガンドで誘起されるシュードノット構造を用いた遺伝発現制御システムの開発.
78. "[Asako Murata,Yasue Harada,Takeo Fukuzumi,Shiori Umemoto,Seongwang Im,Masaki Hagihara,Kazuhiko Nakatani]", Fluorescent indicator displacement assay for the discovery of RNA-binding ligands, 第34回分子生物学会年会.
79. "[Yusuke Takashima,Asako Murata,Kazuhiko Nakatani]", Exploration of RNA sequences in pre-miRNA affecting the efficiency of Dicer cleavage reactions by the small molecules binding, The 24th Annual Meeting of the RNA Society (RNA 2019).
80. "[Yusuke Takashima,Asako Murata,Kazuhiko Nakatani]", Exploration and Identification for Small-molecules RNA binding motif by Dicer cleavage reaction and high throughput sequencing, The 2021 International Chemical Congress of Pacific Basin Societies (Pacifichem2021).
81. "[Shiori Umemoto,Seongwang Im,Jinhua Zhang,Masaki Hagihara,Asako Murata,Yasue Harada,Takeo Fukuzumi,Takahiro Wazaki,Shinichi Sasaoka,Kazuhiko Nakatani]", Evaluation of Xanthone and Thioxanthone Derivatives as Fluorescent Displacement Assay Indicator Based on Their Structure-Binding Studies to RNA, 第38回国際核酸化学シンポジウム.
82. "[Anisa Ul'Husna,Asako Murata,Kazuhiko Nakatani]", Effect of Guanine-guanine Mismatch Binding Ligand on Repair Enzymes' reactions in vitro, 第48回国際核酸化学シンポジウム.
83. Dicer切断産物のハイスループットシーケンシングによる RNA-小分子結合モチーフの同定.
84. Dicer切断反応を指標としたRNA結合分子標的配列の網羅的解析.
85. Dicer切断を阻害するRNA結合分子標的配列の網羅的解析.
86. "[Asako Murata,Ayako Sugai,Yasue Harada,Takahiro Otabe,Takeo Fukuzumi,Kazuhiko Nakatani]", Development of potential small-molecule inhibitors of pre-miRNA processing, The 1st Osaka University - EPFL International Symposium.
87. "[Asako Murata,Yasue Harada,Takeo Fukuzumi,Shiori Umemoto,Seongwang Im,Masaki Hagihara,Kazuhiko Nakatani]", Development of a method for detecting small molecule-miRNA interactions, The 16th Annual Meeting of the RNA Society (RNA2011).
88. "[Jun Matsumoto,Jinxing Li,Asako Murata,Chikara Dohno,Kazuhiko Nakatani]", Development of Isoquinoline Ligand Binding to r(CUG) Repeats, XXIII International Round Table on Nucleosides, Nucleotides and Nucleic acids (IRT2018).
89. "[Jun Matsumoto,Jinxing Li,Masayuki Nakamori,Asako Murata,Chikara Dohno,Kazuhiko Nakatani]", Development of Isoquinoline Ligand Binding to r(CUG) Repeats, 第45回国際核酸化学シンポジウム.
90. "[Yusuke Takashima,Asako Murata, Kei Iida,Masatoshi Hagiwara,Kazuhiko Nakatani]", Development of Exploration Method and Informatics analysis for small molecule-RNA pairs., 第48回国際核酸化学シンポジウム.
91. "[Jinxing Li,Jun Matsumoto,Bai Li-Ping,Asako Murata,Chikara Dohno,Kazuhiko Nakatani]", Designing small molecules targeting CUG repeats causing Myotonic Dystrophy type 1, The 22nd Annual Meeting of the RNA Society (RNA2017).
92. "[Asako Murata,Saki Matsumoto,Neva Caliskan,Marina V. Rodnina,Kazuhiko Nakatani]", Controlling -1 ribosomal frameshifting by small molecules in cells, The 23rd SANKEN INTERNATIONAL SYMPOSIUM.
93. "[Qingwen Chen,Asako Murata,Takeshi Yamada,Ayako Sugai,Yasuyuki Matsushita,Kazuhiko Nakatani]", Computer-aided classification of small molecules targeting CAG-repeat DNA, 第48回国際核酸化学シンポジウム.
94. "[Asako Murata,Yusuke Takashima,Ayumu Asai,Kazuhiko Nakatani]", Comprehensive analysis of small molecule-target RNA pairs toward profiling small-molecule binders of RNA, 第44回分子生物学会年会 (MBSJ2020).
95. "[Asako Murata,Yusuke Takashima,Kei Iida,Ayako Sugai,Masatoshi Hagiwara,Kazuhiko Nakatani]", Comprehensive Analysis of Dicer Substrates by High-Throughput Sequencing Identified New Target RNA Motifs for Small Molecules, 第43回分子生物学会年会 (MBSJ2020).
96. Cell-basedスクリーニングによる SARS-CoV-2のフレームシフトシグナルを標的とする小分子の探索.
97. "[Risa Anami,Asako Murata,Kazuhiko Nakatani]", Cell-based screening of chemical libraries for small molecules that target SARS-CoV-2 frameshifting signal, 第48回国際核酸化学シンポジウム.
98. CAGリピートRNAを標的としたナフチリジン-アザキノロン誘導体の機能評価.
99. CAGリピートDNAおよびRNAとナフチリジンーアザキノロン誘導体とのSPRによる結合評価.
100. CAGリピートDNAおよびRNAを標的とした ナフチリジンーアザキノロン誘導体の開発と 転写および翻訳への阻害効果.
101. BzDANPによるRNAプロセシング阻害の速度論的解析.
102. "[Akihiro Sakata,Jinxing Li,Hanping He,Asako Murata,Chikara Dohno,Satoshi Obika,Kazuhiko Nakatani]", Analysis of binding of naphthyridine-azaquinolone derivatives to CAG repeats RNA, The 2015 International Chemical Congress of Pacific Basin Societies (Pacifichem2015).
103. "[Bimolendu Das,Asako Murata,and Kazuhiko Nakatani]", An RNA internal loop of C, U and A/CC motifs specific fluorescence probe ANP77, 第48回国際核酸化学シンポジウム.
104. "[Asako Murata,Takahiro Otabe,Jinhua Zhang,Kazuhiko Nakatani]", A small-molecule inhibitor of pre-miR-29 maturation, The 2015 International Chemical Congress of Pacific Basin Societies (Pacifichem2015).
105. A Novel Riboswitch Strategy by Utilize Mismatch Binding Ligand (MBL).
106. 8位アリール置換型アデニン誘導体の合成とpre-miR-29aに対する結合評価.


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