Kyushu University Academic Staff Educational and Research Activities Database
List of Reports
Yuichiro Hori Last modified dateļ¼š2024.05.01

Professor / Organic Chemistry and Biochemistry / Department of Chemistry / Faculty of Sciences

1. Shahi Imam Reja, Masafumi Minoshima, Yuichiro Hori, Kazuya Kikuchi, Recent advancements of fluorescent biosensors using semisynthetic probes, Biosensors and Bioelectronics, 10.1016/j.bios.2023.115862, 2024.03.
2. Y. Hori, K. Suzuki, Y. Okuno, M. Nagaoka, S. Futaki, Y. Sugiura, The engineering, structure, and DNA binding properties of a novel His4-type zinc finger peptide., Nucleic acids symposium series, 10.1093/nass/44.1.295, No.44, pp.295-296, 2000.01, We have created a novel His4-type zinc finger protein (H4Sp1) engineered by Cys-- > His mutations of the Cys2His2-type zinc finger in transcription factor Sp1. The CD and NMR studies reveal that the His4 domain has Zn(II)-dependent folding properties and similar secondary structures to wild-type Cys2His2 domain. The DNA binding experiments demonstrate that H4Sp1 can bind DNA in a specific way. The present artificial peptide H4Sp1 will provide valuable information about the interaction between a metallopeptide and DNA..