Kyushu University Academic Staff Educational and Research Activities Database
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Rie Sonoi Last modified date:2023.01.16





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Phone
092-802-2805
Country of degree conferring institution (Overseas)
No
Field of Specialization
Biochemical engineering
ORCID(Open Researcher and Contributor ID)
https://orcid.org/0000-0002-8597-8942
Total Priod of education and research career in the foreign country
00years00months
Outline Activities
Establishment of non-invasive and quantitative evaluation methods based on cell characteristics and behaviors
Research
Research Interests
  • 1.Study on quantitative evaluation and regulation of the maturation through the migratory behaviors of human retinal pigment epithelial cells in confluent state (2011-2017).
    2.Study on the development of process and quality control technology for inducing differentiation of human iPS cells into retinal pigment epithelial cells for use in the transplantation (2014-2015).
    3.Study on the development of quantitative and non-invasive evaluation methods to understand drug toxicity in HepaRG aggregates using Optical Coherence Tomography (OCT) (2018-2021).
    4.Study on establishment of quantitative and non-invasive evaluation methods to understand drug toxicity based on the change in the bile canaliculi behaviors of Hepatocytes (2018-2022).
    keyword : confluent state, epithelial cells, non-invasive evaluation, image analysis, regenerative medicine, drug discovery
    2023.01.
Academic Activities
Papers
1. Sonoi, R. and Hagihara Y., Quantitative understanding of HepaRG cells during drug‐induced intrahepatic cholestasis through changes in bile canaliculi dynamics, Pharmacology Research & Perspectives, 10.1002/prp2.960, 2022.05.
2. Sonoi, R. and Hagihara Y., Tight junction stabilization prevents HepaRG cell death in drug-induced intrahepatic cholestasis, Biology Open, 10.1242/bio.058606, 2021.06.
3. Sonoi, R., Yamakawa, T., Nakatani, N., Kokubo, M., and Hagihara, Y., Noninvasive Evaluation of HepaRG Aggregates during Drug‐Induced Intrahepatic Cholestasis Using Optical Coherence Tomography, Advanced Biology, 10.1002/adbi.202000198, 5, 2, 2021.02.
4. Sonoi, R., and Hagihara, Y., Switching of cell fate through the regulation of cell growth during drug-induced intrahepatic cholestasis, Journal of Bioscience and Bioengineering, 10.1016/j.jbiosc.2020.08.004, 130, 6, 659-665, 2020.12.
5. Sonoi, R., Kim, M.H., Yamada, K., and Kino-oka, M., Phenotypic heterogeneity of human retinal pigment epithelial cells in passaged cell populations, Journal of bioscience and bioengineering, 10.1016/j.jbiosc.2017.03.008, 124, 2, 227-233, 2017.08.
6. Sonoi, R., Kim, M.H., and Kino-oka, M., Facilitation of uniform maturation of human retinal pigment epithelial cells through collective movement in culture, Journal of bioscience and bioengineering, 10.1016/j.jbiosc.2015.05.019, 121, 2, 220-226, 2016.02.
7. Sonoi, R., Kim, M.H., and Kino-oka, M., Locational heterogeneity of maturation by changes in migratory behaviors of human retinal pigment epithelial cells in culture, Journal of bioscience and bioengineering, 10.1016/j.jbiosc.2014.05.025, 119, 1, 107-112, 2015.01.
8. Kim, M.H., Sonoi, R., Yamada, K., Inamori, M., and Kino-oka, M., Analysis of locality of early-stage maturation in confluent state of human retinal pigment epithelial cells, Journal of bioscience and bioengineering, 10.1016/j.jbiosc.2012.02.009, 113, 6, 778-781, 2012.06.
Presentations
1. Sonoi, R., Kim, M.H., and Kino-oka, M. , Analysis of maturation of human retinal pigment epithelial cells in confluent state through a measurement of cell migration, Aachen-Osaka Symposium, 2012.12.
Membership in Academic Society
  • The japanese society for regenerative medicine
  • The society for biotechnology
  • Society for Chemical Engineers