Kyushu University Academic Staff Educational and Research Activities Database
List of Papers
Kanaji Sachiko Last modified date:2024.06.03

Associate Professor / Department of Basic Medicine / Faculty of Medical Sciences

1. Jones JA, Wei N, Cui H, Shi Y, Fu G, Rauniyar N, Shapiro R, Morodomi Y, Berenst N, Dumitru CD, Kanaji S, Yates JR, 3rd, Kanaji T, Yang XL, Nuclear translocation of an aminoacyl-tRNA synthetase may mediate a chronic "integrated stress response", Cell Rep, 10.1016/j.celrep.2023.112632, 42, 6, 112632, 2023.06.
2. Kanaji T, Morodomi Y, Kanaji S, Circulating immune cells with megakaryocyte signature in response to COVID-19 mRNA vaccination, Thromb Res, 10.1016/j.thromres.2022.10.003, 220, 1, 2022.12.
3. Morodomi Y, Kanaji S, Sullivan BM, Zarpellon A, Orje JN, Won E, Shapiro R, Yang XL, Ruf W, Schimmel P, Ruggeri ZM, Kanaji T, Inflammatory platelet production stimulated by tyrosyl-tRNA synthetase mimicking viral
infection, Proc Natl Acad Sci U S A, 10.1073/pnas.2212659119, 119, 48, e2212659119, 2022.11.
4. Kanaji S, Morodomi Y, Weiler H, Zarpellon A, Montgomery RR, Ruggeri ZM, Kanaji T, The impact of aberrant von Willebrand factor-GPIbα interaction on megakaryopoiesis and platelets in humanized type 2B von Willebrand disease model mouse, Haematologica, 10.3324/haematol.2021.280561, 107, 9, 2133, 2022.09.
5. Nakamura T, Morodomi Y, Kanaji S, Okamura T, Nagafuji K, Kanaji T, Detection of anti-GPIbα autoantibodies in a case of immune thrombocytopenia following COVID-19 vaccination, Thromb Res, 10.1016/j.thromres.2021.11.030, 209, 80, 2022.01.
6. Sun J, Uchiyama S, Olson J, Morodomi Y, Cornax I, Ando N, Kohno Y, Kyaw MMT, Aguilar B, Haste NM, Kanaji S, Kanaji T, Rose WE, Sakoulas G, Marth JD, Nizet V, Repurposed drugs block toxin-driven platelet clearance by the hepatic Ashwell-Morell receptor to clear Staphylococcus aureus bacteremia, Sci Transl Med , 10.1126/scitranslmed.abd6737, 13, 586, eabd6737, 2021.03.
7. Won E, Morodomi Y, Kanaji S, Shapiro R, Vo MN, Orje JN, Thornburg CD, Yang XL, Ruggeri ZM, Schimmel P, Kanaji T , Extracellular tyrosyl-tRNA synthetase cleaved by plasma proteinases and stored in platelet alpha-granules: Potential role in monocyte activation, Res Pract Thromb Haemost, 10.1002/rth2.12429, 4, 7, 1167, 2020.09.
8. Lohmeier HK, Slobodianuk TL, Kanaji S, Haberichter SL, Montgomery RR, Flood VH, von Willebrand factor variant D1472H has no effect in mice with humanized VWF-platelet interactions, Blood Adv, 10.1182/bloodadvances.2020002629, 4, 17, 4065, 2020.09.
9. Morodomi Y, Kanaji S, Won E, Ruggeri ZM, Kanaji T, Mechanisms of anti-GPIbalpha antibody-induced thrombocytopenia in mice, Blood, 10.1182/blood.2019003770, 135, 25, 2292, 2020.06.
10. Morodomi Y, Kanaji S, Won E, Kawamoto T, Kanaji T, Modified application of Kawamoto's film method for super-resolution imaging of megakaryocytes in undecalcified bone marrow, Res Pract Thromb Haemost , 10.1002/rth2.12276, 4, 1, 86, 2019.11.
11. Kanaji S, Orje JN, Kanaji T, Kamikubo Y, Morodomi Y, Chen Y, Zarpellon A, Eberhardt J, Forli S, Fahs SA, Sood R, Haberichter SL, Montgomery RR, Ruggeri ZM, Humanized GPIbalpha-von Willebrand factor interaction in the mouse, Blood Adv, 10.1182/bloodadvances.2018023507, 2, 19, 2522, 2018.10.
12. Kanaji T, Vo MN, Kanaji S, Zarpellon A, Shapiro R, Morodomi Y, Yuzuriha A, Eto K, Belani R, Do MH, Yang XL, Ruggeri ZM, Schimmel P, Tyrosyl-tRNA synthetase stimulates thrombopoietin-independent hematopoiesis accelerating recovery from thrombocytopenia, Proc Natl Acad Sci U S A, 10.1073/pnas.1807000115, 115, 35, E8228, 2018.08.
13. Jacobi PM, Kanaji S, Jakab D, Gehrand AL, Johnsen JM, Haberichter SL, von Willebrand factor propeptide to antigen ratio identifies platelet activation and reduced
von Willebrand factor survival phenotype in mice
, J Thromb Haemost, 10.1111/jth.13934, 16, 3, 546, 2018.03.
14. Kanaji S, Fahs SA, Ware J, Montgomery RR, Shi Q, Non-myeloablative conditioning with busulfan before hematopoietic stem cell transplantation leads to phenotypic correction of murine Bernard- Soulier syndrome, J Thromb Haemost, 10.1111/jth.12673, 12, 10, 1726, 2014.10.
15. Kanaji T, Kanaji S, Montgomery RR, Patel SB, Newman PJ, Platelet hyperreactivity explains the bleeding abnormality and macrothrombocytopenia in a murine model of sitosterolemia, Blood, 10.1182/blood-2013-06-510461, 122, 15, 2732, 2013.10.
16. Kanaji S, Fahs SA, Shi Q, Haberichter SL, Montgomery RR, Contribution of platelet vs. endothelial VWF to platelet adhesion and hemostasis, J Thromb Haemost, 10.1111/j.1538-7836.2012.04797.x, 10, 8, 1646, 2012.08.
17. Kanaji S, Kuether EL, Fahs SA, Schroeder JA, Ware J, Montgomery RR, Shi Q, Correction of murine Bernard-Soulier syndrome by lentivirus-mediated gene therapy, Mol Ther, 10.1038/mt.2011.231, 20, 3, 625, 2012.03.
18. Ito T, Suzuki S, Kanaji S, Shiraishi H, Ohta S, Arima K, Tanaka G, Tamada T, Honjo E, Garcia KC, Kuroki R, Izuhara K , Distinct structural requirements for interleukin-4 (IL-4) and IL-13 binding to the shared IL-13 receptor facilitate cellular tuning of cytokine responsiven, J Biol Chem 284 , 10.1074/jbc.M109.007286, 284, 36, 24289, 2009.09.
19. Kanaji S, Kanaji T, Honda M, Nakazato S, Wakayama K, Tabata Y, Shibata S, Gondo H, Nakamura I, Node K, Miura M, Miyahara M, Okamura T, Nagumo F, Ohta S, Izuhara K, Identification of four novel mutations in F5 associated with congenital factor V deficiency, Int J Hematol, 10.1007/s12185-008-0210-4, 89, 1, 71, 2009.01.
20. Sonoda E, Aoki S, Uchihashi K, Soejima H, Kanaji S, Izuhara K, Satoh S, Fujitani N, Sugihara H, Toda S , A new organotypic culture of adipose tissue fragments maintains viable mature adipocytes for a long term, together with development of immature adipocytes and mesenchymal stem cell-like cells, Endocrinology, 10.1210/en.2008-0525, 149, 10, 4794, 2008.10.
21. Honjo E, Shoyama Y, Tamada T, Shigematsu H, Hatanaka T, Kanaji S, Arima K, Ito Y, Izuhara K, Kuroki R , Expression of the extracellular region of the human interleukin-4 receptor alpha chain and interleukin-13 receptor alpha1 chain by a silkworm-baculovirus system, Protein Expr Purif, 10.1016/j.pep.2008.03.020, 60, 1, 25, 2008.07.
22. Nakao I, Kanaji S, Ohta S, Matsushita H, Arima K, Yuyama N, Yamaya M, Nakayama K, Kubo H, Watanabe M, Sagara H, Sugiyama K, Tanaka H, Toda S, Hayashi H, Inoue H, Hoshino T, Shiraki A, Inoue M, Suzuki K, Aizawa H, Okinami S, Nagai H, Hasegawa M, Fukuda T, Green ED, Izuhara K , Identification of pendrin as a common mediator for mucus production in bronchial asthma and chronic obstructive pulmonary disease, J Immunol, 10.4049/jimmunol.180.9.6262, 180, 9, 6262, 2008.05.
23. Kanaji S, Kanaji T, Migita M, Kunishima S, Kunicki TJ, Okamura T, Izuhara K, Characterization of a patient with atypical amegakaryocytic thrombocytopenia, Eur J Haematol, 10.1111/j.1600-0609.2008.01029.x, 80, 4, 361, 2008.04.
24. Kanaji S, Tanaka Y, Sakata Y, Takeshita K, Arima K, Ohta S, Hansell EJ, Caffrey C, Mottram JC, Lowther J, Donnelly S, Stack C, Kadowaki T, Yamamoto K, McKerrow JH, Dalton JP, Coombs GH, Izuhara K, Squamous cell carcinoma antigen 1 is an inhibitor of parasite-derived cysteine proteases, FEBS Lett, 10.1016/j.febslet.2007.07.072, 581, 22, 4260, 2007.09.
25. Cheli Y, Kanaji S, Jacquelin B, Chang M, Nugent DJ, Kunicki TJ, Transcriptional and epigenetic regulation of the integrin collagen receptor locus ITGA1-PELO-ITGA2, Biochim Biophys Acta, 10.1016/j.bbaexp.2007.06.004, 1769, 9-10, 546, 2007.09.
26. Goda C, Kanaji T, Kanaji S, Tanaka G, Arima K, Ohno S, Izuhara K, Involvement of IL-32 in activation-induced cell death in T cells
, Int Immunol, 10.1093/intimm/dxh339, 18, 2, 233, 2006.02.
27. Arima K, Sato K, Tanaka G, Kanaji S, Terada T, Honjo E, Kuroki R, Matsuo Y, Izuhara K, Characterization of the interaction between interleukin-13 and interleukin-13 receptors, J Biol Chem, 10.1074/jbc.M502571200, 280, 26, 24915, 2005.07.
28. Tanaka G, Kanaji S, Hirano A, Arima K, Shinagawa A, Goda C, Yasunaga S, Ikizawa K, Yanagihara Y, Kubo M, Kuriyama-Fujii Y, Sugita Y, Inokuchi A, Izuhara K, Induction and activation of the aryl hydrocarbon receptor by IL-4 in B cells, Int Immunol, 10.1093/intimm/dxh260, 17, 6, 797, 2005.06.
29. Kanaji S, Kanaji T, Jacquelin B, Chang M, Nugent DJ, Komatsu N, Moroi M, Izuhara K, Kunicki TJ, Thrombopoietin initiates demethylation-based transcription of GP6 during megakaryocyte differentiation, Blood, 10.1182/blood-2004-08-3109, 105, 10, 3888, 2005.05.
30. Kanaji S, Kanaji T, Furihata K, Kato K, Ware JL, Kunicki TJ, Convulxin binds to native, human glycoprotein Ib alpha, J Biol Chem, 10.1074/jbc.M300199200, 278, 41, 39452, 2003.10.
31. Kato K, Kanaji T, Russell S, Kunicki TJ, Furihata K, Kanaji S, Marchese P, Reininger A, Ruggeri ZM, Ware J, The contribution of glycoprotein VI to stable platelet adhesion and thrombus formation illustrated by targeted gene deletion, Blood, 10.1182/blood-2003-03-0717, 102, 5, 1701, 2003.09.
32. Kanaji T, Kanaji S, Osaki K, Kuroiwa M, Sakaguchi M, Mihara K, Niho Y, Okamura T, Identification and characterization of two novel mutations (Q421 K and R123P) in congenital factor XII deficiency, Thromb Haemost, 86, 6, 1409, 2001.12.
33. Jacquelin B, Rozenshteyn D, Kanaji S, Koziol JA, Nurden AT, Kunicki TJ, Characterization of Inherited Differences in Transcription of the Human Integrin alpha 2 Gene, J Biol Chem , 10.1074/jbc.M102019200, 276, 26, 23518, 2001.06.
34. Kanaji S, Iwahashi J, Kida Y, Sakaguchi M, Mihara K, Characterization of the signal that directs Tom20 to the mitochondrial outer membrane, J Cell Biol, 10.1083/jcb.151.2.277, 151, 2, 277, 2000.10.
35. Kanaji S, Okuma K, Tokumitsu Y, Yoshizawa S, Nakamura M, Niho Y, Hemophagocytic syndrome associated with fulminant ulcerative colitis and presumed acute pancreatitis, Am J Gastroenterol, 0.1111/j.1572-0241.1998.00554.x, 93, 10, 1956, 1998.10.
36. Takaoka (Kanaji) S, Higuchi M, Odashiro K, Yoshizawa S, Horiuchi T, Niho Y, Severe left ventricular dysfunction in a patient with primary Sjogren's syndrome, 日本臨床免疫学会会誌, 10.2177/jsci.20.199, 20, 3, 199, 1997.06.