|Ken-ichirou Morohashi||Last modified date：2021.05.21|
Professor / Biology of sex differences / Department of Molecular Biology / Faculty of Medical Sciences
|Ken-ichirou Morohashi||Last modified date：2021.05.21|
|1.||Antonius Christianto, Takashi Baba, Fumiya Takahashi, Kai Inui, Mikita Suyama, Yasuyuki Ohkawa, Ken-Ichirou Morohashi , SEX DIFFERENCES IN MOUSE SKELETAL MUSCLE, 分子生物学会, 2019.12.|
|2.||Antonius Christianto, Fumiya Takahashi, Takashi Baba, Ken-Ichirou Morohashi, SEX DIFFERENCES OBSERVED IN MOUSE SKELETAL MUSCLE, ステロイドホルモン 学会, 2019.11.|
|3.||Ken Morohashi, Miki Inoue, Takashi Baba, Ad4BP/SF-1 more than a regulator of adrenal steroids, 34th Joint Annual Conference of Biomedical Sciences,, 2019.03.|
|4.||Ken-chirou Morohashi, Ad4BP/SF-1 more than a regulator of adrenal steroids, 18th International Congress of Endocrinology, 2018.12.|
|5.||Ken Morohashi, Orchestration of housekeeping and cell-specific metabolisms in steroidogenic cells by a transcription factor Ad4BP/SF-1, The 18th Japan-Italy Symposium The front line of research into gender science, 2018.10.|
|6.||Ken-ichirou Morohashi, Genetic and Endocrine Regulation of Gonadal Sex, The 18th Congress of the International Society for Gender Medicine, 2017.09.|
|7.||Ken-ichirou Morohashi, History of fetal Leydig cells, ENDO 2017, 2017.04.|
|8.||Takashi Baba, Miki Inoue, Bing Li, Ken-ichirou Morohashi, Regulation of metabolism in steroidogenic cells by Ad4BP/SF-1., The 32nd International Kumamoto Medical Bioscience Symposium, 2016.06.|
|9.||Takashi Baba, Hiroyuki Otake, Yasuhiro Ishihara, Man-Ho Choi, Miki Inoue, Yurina Shishido, Kanako Miyabayashi, Yuichi Shima and Ken-ichirou Morohashi, Regulation of de novo cholesterol synthesis by a nuclear receptor Ad4BP/SF-1, 17th Adrenal Cortex Conference, 2016.03.|
|10.||馬場 崇, Ken-ichirou Morohashi, Regulation of de novo cholesterol synthesis by a nuclear receptor Ad4BP/SF-1, 19th International conference on Cytochrome P450, 2015.06.|
|11.||Takashi Baba, 大竹 博之, 宮林 香奈子, Yuichi Shima, Ken-ichirou Morohashi, Dual Roles of Ad4BP/SF-1 in Steroidogenesis and Glycolysis, 39th Annual meeting of Japan Society for Comparative Endocrinology 8th International Symposium on Amphibian and Reptile Endocrinology and Neurobiology, 2014.11.|
|12.||Ken-ichirou Morohashi, A Novel Landscape of Target Genes for Ad4BP/SF-1. , Endocrine Society’s 95th Annual Meeting, 2013.06.|
|13.||Yuichi Shima, 宮林 香奈子, Takashi Baba, 大竹 博之, 松崎 佐和子, 宍戸 祐里菜, 井上 実紀, Shogo Haraguchi, Yoshikazu Tsutsui, Ken-ichirou Morohashi, Functional interplay between Leydig and Serotoli cells is essential for testosterone biosynthesis in mouse fetal testis, The 15th International Congress on Hormonal Steroids and Hormones & Cancer, 2012.11.|
|14.||Ken-ichirou Morohashi, Glycolytic genes as the targets of Ad4BP/SF-1, 15th Conference on the adrenal cortex, Adrenal 2012, , 2012.06.|
|15.||Yuichi Shima, 宮林 香奈子, Takashi Baba, 大竹 博之, Kentaro Suzuki, Shogo Haraguchi, Ken-ichirou Morohashi, Functional characterization of fetal Leydig cells by cell-specific disruption of Ad4BP/SF-1 gene, Sixth International Symposium on the Biology of Vertebrate Sex Determination, 2012.04.|
|16.||Ken-ichirou Morohashi, Molecular and Cellular Mechanisms of Testis Differentiation, Gordon Research Conference, 2010 Reproductive Tract Biology, 2010.08.|
|17.||Fatchiyah, M. Zubair, Ken-Ichirou Morohashi, Revealing Spleen Ad4BP/SF1 Knockout Mouse by BAC-Ad4BP-tTAZ Transgene, 13th International Conference on Biomedical Engineering, ICBME 2008, 2009.12, The purpose of this study is addressed the function of Ad4BP/SF1 in developing spleen of Ad4BP/SF-1 KO mouse. I have modified the BAC-Ad4BP endogenous by homologous recombinant with modification cassette-containing tetracycline transactivator system and LacZ reporter genes to allow the expression of Ad4BP/SF1 in developing tissues and organ differentiation, regulate of Ad4BP/SF1 mechanism, and reveal the defect due to Ad4BP/SF1 deficiency. Recently studies, by immunihistochemistry of adult tissues showed that revealed coincident expressing between Ad4BP/SF-1 and lacZ, indicating the tTA system seemed to reproduces the endogenous expression of Ad4BP/SF-1, and thus likely to lacZ, Ad4BP/SF-1 in the BAC transgene was expected to be expressed in the corresponding tissues under the control of the bidirectional promoter. Interestingly, the BAC-Ad4BP-tTA transgenic mice were succeeded to up regulate the expression of Ad4BP/SF-1 at the protein level than wild type. And the fetal spleen of Tg(+);Ad4(+/+) was larger than that of the wild type, and expectedly the size of the spleen of Tg(+);Ad4(-/-) apparently recovered..|
|18.||H. Ogawa, T. Komatsu, K. Morohashi
"Purification and analysis of a factor interacting with sumoylated Ad4BP/SF-1"
Dec 14, 2007, Workshop "Regulation and biology of the SUMO Conjugation and De-confugation system" in BMB (Biochemistry and Molecular Biology) 2007, Pacifico Yokohaha, Yokohama.
|19.||M. Kusaka, Y. katoh-Fukui, H. Ogawa, K. Miyabayashi, Y. Sugimoto, Y. Okuno, A. Kogo, S. Aizawa, K. Morohashi
"Enx2 regulates coelomic epithelial cell polarity via regulation of EGFR"
Dec 14, 2007, BMB (Biochemistry and Molecular Biology) 2007, Pacifico Yokohaha, Yokohama.
|20.||Y. Ishimaru, H. Yoshioka, M. Kasahara, Y. Kato-Fukui, K. Morohashi "Identification and characterization of chick sex determination gene"
Dec 13, 2007, BMB (Biochemistry and Molecular Biology) 2007, Pacifico Yokohaha, Yokohama.
|21.||T. Baba, J. Y. Shima, A. Owaki, J. Mimura, M. Oshima, Y. Fujii-Kuriyama, K. Morohashi "Disruption of the aryl hydrocarbon receptor (AhR) induces regression of the seminal vesicle in aged male mice"
Dec 12, 2007, BMB (Biochemistry and Molecular Biology) 2007, Pacifico Yokohaha, Yokohama.
|22.||Ken-ichirou Morohashi "Molecular Mechanism of Ad4BP/SF-1 on Sex Differentiation"
International Conference of Molecular Biology of Life Sciences 2007
Nov 19, 2007, Convention Hall of Widyaloka Brawijaya University ,Malang, Indonesia.
|23.||From Ad4BP/SF-1 to cell and tissue differentiation..|
|24.||Regulation of Ad4BP/SF-1 by SUMO.|
|25.||Takashi Baba, Ken-ichirou Morohashi, Dual Roles of Ad4BP/SF-1 in Steroidogenesis and Glycolysis, 20th International Symposium on Microsomal and Drug Oxidations.|
|26.||Takashi Baba, Ken-ichirou Morohashi, The function of Ad4BP/SF-1 in adrenocortical metbolism, 16th Conference on the adrenal cortex, Adrenal 2014.|