| 1. |
Shinsuke Fujii, Kana Hasegawa, Takashi Maehara, Kari J. Kurppa, Kristiina Heikinheimo, Kristy A. Warner, Satoshi Maruyama, Yudai Tajiri, Jacques E. Nör, Jun-ichi Tanuma, Shintaro Kawano, Tamotsu Kiyoshima., Wnt/β-catenin-C-kit axis may play a role in adenoid cystic carcinoma prognostication, Pathol Res Pract., 2024.01. |
| 2. |
Thinh Thi Kim Truong, Shinsuke Fujii, Ryoko Nagano, Kana Hasegawa, Megumi Kokura, Yuta Chiba, Keigo Yoshizaki, Satoshi Fukumoto, Tamotsu Kiyoshima , Arl4c is involved in tooth germ development through osteoblastic/ameloblastic differentiation, Biochem Biophys Res Commun., 2023.10. |
| 3. |
Dania Zuhier Ragheb Alkhatib, Thinh Thi Kim Truong, Shinsuke Fujii, Kana Hasegawa, Ryoko Nagano, Yudai Tajiri, Tamotsu Kiyoshima, Stepwise activation of p63 and the MEK/ERK pathway induces the expression of ARL4C to promote oral squamous cell carcinoma cell proliferation, Pathology - Research and Practice, 2023.04, 口腔癌の90％以上を口腔扁平上皮癌（OSCC）が占める。組織学的にOSCCは粘膜上皮の過形成から始まり、上皮性異型性、上皮内癌、浸潤癌へと複数の段階を経て進行する。すなわち、OSCCの発症には遺伝子変化を介した多段階発癌が関与すると考えられるが、その詳細なメカニズムは不明である。本研究では、p63およびMAPK経路の段階的な活性化がARL4Cの発現制御を介して、OSCCの細胞増殖に関与することを示唆した。. |
| 4. |
Ryoko Nagano, Shinsuke Fujii, Kana Hasegawa, Hidefumi Maeda, Tamotsu Kiyoshima, Wnt signaling promotes tooth germ development through YAP1-TGF-β signaling, Biochem Biophys Res Commun., 2022.11. |
| 5. |
Kana Hasegawa, Shinsuke Fujii, Kari J Kurppa, Takashi Maehara, Kazunari Oobu, Seiji Nakamura, Tamotsu Kiyoshima, Clear cell squamous cell carcinoma of the tongue exhibits characteristics as an undifferentiated squamous cell carcinoma, Pathol Res Pract., 2022.06. |
| 6. |
Kana Hasegawa, Shinsuke Fujii , Shinji Matsumoto, Yudai Tajiri, Akira Kikuchi and Tamotsu Kiyoshima, YAP signaling induces PIEZO1 to promote oral squamous cell carcinoma cell proliferation, JOURNAL OF PATHOLOGY, 10.1002/path.5553, 2020.11.  |
