| 1. |
Daisuke Itoh, Fumihiro Sassa, Taiji Nishi, Yoko Kani, Masakazu Murata, Hiroaki Suzuki, Droplet-based microfluidic sensing system for rapid fish freshness determination, Sensors and Actuators B: Chemical, 10.1016/j.snb.2012.05.043, 171-172, 619-626, 2012.08. |
| 2. |
Tomomi Sakata, Fumihiro Sassa, Mitsuo Usui, Junichi Kodate, Hiromu Ishii, Katsuyuki Machida, Yoshito Jin, Monolithically integrated MEMS mirror array with low electrical interference in wavelength-selective switches, Precision Engineering, 10.1016/j.precisioneng.2013.05.008, 37, 4, 897-901, 2013.10, This paper describes the fabrication of a microelectromechanical-system (MEMS) mirror array for a wavelength-selective switch (WSS). The MEMS mirror array, in which a lot of closely spaced adjacent mirrors are electrostatically operated, consists of a MEMS mirrors and a mirror-drive electrodes. In order to reduce electrical interference, comb-shaped ground walls with a high aspect ratio of about 20 are monolithically integrated with the MEMS mirror chip. Further, U-shaped gold electroplating walls are formed in the mirror-drive electrode chip. With these walls, each MEMS mirror successfully operates with low electrical interference. © 2013 Elsevier Inc. All rights reserved.. |
| 3. |
Satoshi Araki, Masashi Watanabe, Fumihiro Sassa, Kenshi Hayashi, Raman enhanced structure with reconfigured molecularly-imprinted-polymer for gas deteciton, Proceedings of IEEE Sensors, 10.1109/ICSENS.2016.7808604, 2017.01, Various devices are developed to obtain information of odor for crisis evasion in dangerous situation. However, the improvement of sensing methodology is lagging. Therefore, some novel odor sensors with high sensitivity, selectivity and short response time are required. Gas detection based on surface enhanced Raman scattering (SERS) is a promising technology to realize such sensor. We developed a sandwich structured SERS substrate with an organic layer, which was placed between an Au thin layer and a gold nano particles (AuNPs) layer. Furthermore, the organic layer was reconfigured to molecularly imprinted polymer (MIP) for selective gas detection. Raman spectrum obtained with a MIP-SERS substrate shows the appearance of peak based on 2-phenylethanol that is targeted gas molecule. Compared with non-imprinted polymer (NIP), MIP substrate showed stronger SERS signals.. |
| 4. |
Keigo Nakanishi, Fumihiro Sassa, Kenshi Hayashi, Photo-tunable molecular recognizing smart material for gas sensing, TRANSDUCERS 2017 - 19th International Conference on Solid-State Sensors, Actuators and Microsystems, 10.1109/TRANSDUCERS.2017.7994313, 1376-1379, 2017.07, We developed a dynamic photo-tunable gas adsorbent based on smart (photo sensitive) material and molecularly imprinted polymer (MIP) technology [1]. Gas adsorption property of the material, mixture of photochromic materials and polymethyl methacrylate (PMMA), can be controlled reversible and continuously by irradiation of with light different wavelength. As a result, gas sensor which is composed of a quartz crystal microbalance (QCM) coated with the developed adsorbent was fabricated. This sensor system can detect a certain gas molecule corresponding to the adsorbent property from gas mixture with only one sensor node.. |
| 5. |
Hiro-Taka Yoshioka, Shota Ueno, Sassa Fumihiro, Kenshi Hayashi, Odorants measurement using hyperspectral imaging and PVC film including multi fluorescent probes, 2017 IEEE SENSORS, 10.1109/ICSENS.2017.8234328, 2017-December, 1-3, 2017.12. |
| 6. |
Sho Shinohara, Fumihiro Sassa, Kenshi Hayashi, Gas selective chemiresistor composed of molecularly imprinted polymer composit ink, Proceedings of IEEE Sensors, 10.1109/ICSENS.2016.7808660, 2017.01, Gas sensor with high molecular selectivity is highly demanded in many fields of industry or disaster relief. Molecularly imprinted polymer (MIP) can recognize target gas by specific adsorption for template molecule. In this study, a novel chemiresistor, gas sensor which combined with MIP and conductive nanoparticles has been developed. The gases were distinguished based on molecularly structure by MIP. If gas molecule is absorbed into this polymer, structures and properties of conductive composites are changed. It causes electric resistance changed. It is conceivable that the degree of resistance change is dependent upon the amount of absorption. Moreover, MIP absorbs larger quantity of template molecule than similar gas molecule. So this MIP chemiresistor can be used for measurement of specific target gas based on magnitude of response. Measurement results of gas sensing showed that larger response was produced by MIP chemiresistor for the template molecule than other gas and NIP (non-imprinted polymer) composite. It means that a sensor which could both recognizing molecules and transduce electrical signal simultaneously was successfully developed.. |
| 7. |
Masashi Watanabe, Fumihiro Sassa, Kenshi Hayashi, Formation of oriented metal nanostructures by polarized light irradiation for optical sensing, Proceedings of IEEE Sensors, 10.1109/ICSENS.2016.7808850, 2017.01, Highly sensitive optical sensing of molecules can be achieved by using localized surface plasmon generated at metal nanostructures, such as SERS-based sensing. We fabricated SERS-active silver nanostructures by using polarized light irradiation, and evaluated their response properties to rhodamine 6G. In this paper, it is shown that strong Raman signals of rhodamine 6G and large variation in optical transmission have been obtained. Especially, the transmission spectra of the silver nanostructures grown under the irradiation of polarized light showed unique polarizing properties derived from different modes of localized surface plasmons, which would be useful in smart optical sensing.. |
| 8. |
Zhongyuan Yang, Takaaki Soeda, Fumihiro Sassa, Kenshi Hayashi, Visualization of Spatial Distribution of on Ground Gas Sources with LSPR based 1D/2D High Speed Gas Sensor Robot System, Proceedings of IEEE Sensors, 10.1109/ICSENS.2018.8589909, 2018-October, 2018.12, Various odor robots have been developed for gas source localization in plume with specific algorithm. However, sensor response speed is now a major limit for the promotion of odor robot using chemical substances information. In this research, we have fabricated a Localized surface plasmon resonance based gas sensor which can show a quick response to gas molecular at a high speed of above 25Hz. The sensor was mounted on a mobile robot for gas sources detection successfully. Furthermore, a two-dimensional gas sensor based on the same technique was developed for visualization of spatial distribution of gas flow.. |
| 9. |
Xiaoguang Ying, Hiro Taka Yoshioka, Chuanjun Liu, Fumihiro Sassa, Kenshi Hayashi, Molecular imprinting technique in putrescine visualized detection, Sensors and Actuators, B: Chemical, 10.1016/j.snb.2017.11.128, 258, 870-880, 2018.04, This work is an exploration into visualizing measurement of putrescine specific adsorption by photographing colorized molecule imprinting chromogenic hydrogel. Membranes are prepared with imitate templates 1,4-butylene glycol, adipic acid or succinic acid, respectively and ninhydrin is used as chromogenic agent for target molecule putrescine. The adsorbing concentration on MIP is reflected in the form of visible violet-colored stain differed in shape and shade, which are recorded by hyper spectral camera and proceeded into intuitive 3D isohypse surfaces plot. By quantifying the height of surface peaks, imprinting efficiency is estimated in accordance with polyvinyl alcohol concentration and crosslinking degree. The imprinting efficiency of three imitate molecule templates is also discussed.. |
| 10. |
Fumihiro Sassa, Kenshi Hayashi, Flexible Thermal Actuator Film for Monolithic Soft Micro Robot Process, Proceedings of IEEE Sensors, 10.1109/ICSENS.2018.8589717, 2018-October, 2018.12, Patternable actuator film for monolithic soft micro robot process was developed. The film is consisted from thermal bimorph actuation layer and extra functional layer including driving heater layer and elastic mechanical buffer layer. A cantilever arm actuator fabricated by patterning the film was operated with 2 V applied voltage. Multi actuator device or micro robot can be fabricated without assembling process by appropriate patterning process with this film.. |
| 11. |
Wu Shuanghong, Fumihiro Sassa, Kenshi Hayashi, An Odor Visualization Film Based on Multi Colors Fluorescent Microbeads and Single Color Fluorescent Multi Microbeads, Proceedings of IEEE Sensors, 10.1109/ICSENS.2018.8589830, 2018-October, 2018.12, The microbeads shape sensor film was developed in this work combines fluorescent dye agents whose fluorescent intensity can be influenced in touch of a specific odor, and Molecular Imprinting Polymer. Like photographic films, the fluorescent dye microbeads film can visualize the odor gas diffusion with the CCD camera. To enhance the fluorescence intensity of Quinine Sulfate increases in the water environment, hydrogel was applied in the film. For developing multi-odor sensors, we made four kinds of fluorescent microbeads to test whether the interaction among fluorescent dyes happened. It turned out microbeads structure successfully remained characters of every fluorescent dye.. |
| 12. |
Fumihiro Sassa, Chuanjun Liu, Kenshi Hayashi, Visualization of odor space and quality, Chemical, Gas, and Biosensors for Internet of Things and Related Applications, 10.1016/B978-0-12-815409-0.00018-8, 253-269, 2019.01, Our living environment is surrounded by a variety of odors. The visualized detection of odorant molecules may explore many new applications that cannot be realized by conventional sensors. This chapter introduces some novel sensing technologies that can be used to visualize both the odor space and odor quality. Fluorescence imaging sensors are developed to record the shape of odor sources and the spatiotemporal distribution of odor flows. Multispectral imaging-based odor visualization shows power in the structure-related discrimination of different odorant molecules. Localized surface plasmon resonance (LSPR) sensors based on metal nanoparticles show advantages in high-speed response and recovery in gas or vapor sensing. A sensor robot based on the LSPR sensors is developed to visualize the odor information from on-ground odor sources. In addition, data analysis based on physicochemical parameters of odorant molecules is carried out to demonstrate the difference of odor quality by using network-graph techniques.. |
| 13. |
Takaaki Soeda, Zhongyuan Yang, Zheng Xiofan, Fumihiro Sassa, Yoichi Tomiura, Kenshi Hayashi, Two dimensional LSPR gas sensor with Au/Ag core-shell structure, ISOEN 2019 - 18th International Symposium on Olfaction and Electronic Nose, Proceedings, 10.1109/ISOEN.2019.8823375, 2019.05, If we can quickly recognize the distribution of dangerous gases, it will be useful in places such as disaster scene. Localized surface plasmon resonance (LSPR) gas sensor is known as a gas sensor with high response / recovery speed and high spatial resolution. However, the general LSPR gas sensor does not have a molecular selectivity and it is difficult to identify the gas species. We made gas selected pixelated LSPR substrate based on Au/Ag core-shell structure by photo-induced growth by exposure system using the photomask.. |
| 14. |
Hao Guo, Takaaki Soeda, Zhongyuan Yang, Fumihiro Sassa, Kenshi Hayashi, Probe gas sensing system based on reflected light detection from localized surface plasmon resonance, 2019 IEEE International Symposium on Olfaction and Electronic Nose (ISOEN), 10.1109/ISOEN.2019.8823157, 2019.05. |
| 15. |
Zhongyuan Yang, Takaaki Soeda, Fumihiro Sassa, Kenshi Hayashi, Odor Trace Visualization by Mobile Robot Equipped with Two-Dimensional LSPR Gas Sensor, 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII), 10.1109/TRANSDUCERS.2019.8808400, 1203-1206, 2019.06. |
| 16. |
Shota Shimizu, Liang Shang, Fumihiro Sassa, Kenshi Hayashi, Multiplexed LSPR gas sensor with an arrayed molecularly imprinted Sol-Gel filter, ISOEN 2019 - 18th International Symposium on Olfaction and Electronic Nose, Proceedings, 10.1109/ISOEN.2019.8823275, 2019.05, Detection of volatile organic components (VOCs) is meaningful to agricultural field, bio recognition and so on. In this study, we developed an array type gas sensor to detect VOCs. This sensor is based on localized surface plasmon resonance (LSPR). Molecularly Imprinted Sol-Gels (MISG) were patterned on the surface of Au nano-islands to add molecular selectivity. The substrate is separated into 9 regions on AuNPs by using polyimide tape partitions and spin coating MISG solutions for each region. Multi channels sensor was fabricated with this substrate after this process. The sensor's sensitives were compared for each channel. The result indicated that the sensitivity of target gas channel was higher than into others.. |
| 17. |
Lin Chen, Bin Chen, Fumihiro Sassa, Kenshi Hayashi, Multi-layer Filter Structure for Molecular Selective SERS Gas Sensor, Proceedings of IEEE Sensors, 10.1109/SENSORS43011.2019.8956884, 2019-October, 2019.10, Mixture of gas molecules must be accurately detected for gas sensor. However, there are certain difficulties in identifying the type of gas and detecting its concentration by chemical sensors. SERS (Surface Enhanced Raman Scattering) is a promising method for high sensitive gas detection because of its ability of molecule discrimination. However, it is difficult for SERS sensor to identify gases with the similar structure. In this research, we have developed a more selective SERS sensor with molecular filter layers. Molecular filter property is studied by coating a filter polymer film on the SERS substrate. The characteristics of the sensor with two membrane structures were also studied and different filtering properties were obtained.. |
| 18. |
Yasuhiro Kusuda, Zhongyuan Yang, Takaaki Soeda, Fumihiro Sassa, Kenshi Hayashi, Invisible Odor Trace Tracking with LSPR based High Speed Gas Sensor Robot System, 2019 IEEE SENSORS, 10.1109/SENSORS43011.2019.8956599, 2019-October, 2019.10. |
| 19. |
Lingpu Ge, Bin Chen, Hiroki Kawano, Fumihiro Sassa, Kenshi Hayashi, Inkjet-printed Gas Sensor Matrix with Molecularly Imprinted Gas Selective Materials, Proceedings of IEEE Sensors, 10.1109/SENSORS43011.2019.8956795, 2019-October, 2019.10, This paper introduces a new method to fabricate a large - scale sensor array. By printing electrodes on photographic paper and making insulating layers, 6×6 arrays of sensors were obtained. Different gas selective can be printed in different units to detect different gases. Thus, production of multiple sensors in a small area with low cost was realized. On a piece of A4 photo paper, 30 sensor matrices can be printed at the same time. Each sensor array has 36 sensing units, thus theoretically identifying up to 36 gases. The sensor is suitable to be used in wearable devices to identify human skin gases due to its flexible substrate, low production cost and simple manufacturing process. In this experiment, molecular imprinted polymer (MIP) solution [1], carbon black (C.B.) conductive solution and insulating solution are prepared as ink, which can be used for ink-jet printer printing. This makes the method of developing the sensor more flexible. Compared with the sensor developed by micropipette to drop the MIP solution and C.B. conductive solution, the sensor developed by a printer has better uniformity.. |
| 20. |
Takaaki Soeda, Zhongyuan Yang, Fumihiro Sassa, Kenshi Hayashi, Gas Visualization with Photo-Induced 2D Pixel Patterned Au/Ag Core-Shell LSPR Imaging Device by Mask-Less Exposure System, 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII), 10.1109/TRANSDUCERS.2019.8808591, 1274-1276, 2019.06. |
| 21. |
Lingpu Ge, Fumihiro Sassa, Kenshi Hayashi, Flexible Gas Sensor Array Based on Matrix of Molecularly Imprinted Materials and Full Printing Process, 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII, 10.1109/TRANSDUCERS.2019.8808512, 765-768, 2019.06, This paper proposes a flexible gas sensor array system fabricated by full printing process, which can simultaneously monitor a variety of gases. The production of sensors using a low-cost, large-scale, high-speed printing technology throughout the process. Realizing the production of multiple sensors in a small area with low cost. Detection of a variety of gases using a sensor array. The results show that it is possible to make a full-printing gas sensor by acetylene carbon black (Φ20 nm) ink and molecularly imprinted polymer (MIP) ink; 36 sensors are formed on a 3cm-3cm paper; and the gases such as acetic acid and hexanoic acid are well recognized.. |
| 22. |
Zhongyuan Yang, Takaaki Soeda, Fumihiro Sassa, Kenshi Hayashi, Development of Odor Visualization System with Two-Dimensional LSPR Gas Sensor for Mobile Robot, ISOEN 2019 - 18th International Symposium on Olfaction and Electronic Nose, Proceedings, 10.1109/ISOEN.2019.8823230, 2019.05, Localized Surface Plasmon Resonance (LSPR) based gas sensor is a promising way to break the bottleneck of the sensing speed of traditional semiconductor gas senor for mobile robot use. In this study, we developed a two-dimensional gas visualization system based on LSPR phenomenon with Au/Ag nanoparticles for high speed and high spatial resolution sensing. The 9-hour silver growth on the surface of Au nanoparticles layer has been shown to reduce the influence of transmitted light (noise) on visualization while ensuring sensitivity. An invisible odor trace similar to letter 'U' with a line width of 3 mm was visualized by CCD camera through the LSPR sensor film. The intensity changes of the image every 1 second showed of the developed system's high response speed and spatial resolution.. |
| 23. |
Takaaki Soeda, Zhongyuan Yang, Fumihiro Sassa, Yoichi Tomiura, Kenshi Hayashi, 2D LSPR multi gas sensor array with 4-segmented subpixel using Au/Ag core shell structure, 2019 IEEE SENSORS, 10.1109/SENSORS43011.2019.8956635, 2019-October, 2019.10. |
| 24. |
Lin Chen, Hao Guo, Fumihiro Sassa, Bin Chen, Kenshi Hayashi, Sers gas sensors based on multiple polymer films with high design flexibility for gas recognition, Sensors, 10.3390/s21165546, 21, 16, 2021.08, The Surface-Enhanced Raman Scattering (SERS) technique is utilized to fabricate sensors for gas detection due to its rapid detection speed and high sensitivity. However, gases with similar molecular structures are difficult to directly discriminate using SERS gas sensors because there are characteristic peak overlaps in the Raman spectra. Here, we proposed a multiple SERS gas sensor matrix via a spin-coating functional polymer to enhance the gas recognition capability. Poly (acrylic acid) (PAA), Poly (methyl methacrylate) (PMMA) and Polydimethylsiloxane (PDMS) were employed to fabricate the polymer film. The high design flexibility of the two-layer film was realized by the layer-by-layer method with 2 one-layer films. The SERS gas sensor coated by different polymer films showed a distinct affinity to target gases. The principle component analysis (PCA) algorithm was used for the further clustering of gas molecules. Three target gases, phenethyl alcohol, acetophenone and anethole, were perfectly discriminated, as the characteristic variables in the response matrix constructed by the combination of gas responses obtained 3 one-layer and 3 two-layer film-coated sensors. This research provides a new SERS sensing approach for recognizing gases with similar molecular structures.. |
| 25. |
C. Duran, S. Zhang, C. Yang, M. L. Falco, C. Cravo-Laureau, C. Suzuki-Minakuchi, H. Nojiri, R. Duran, F. Sassa, Low-cost gel-filled microwell array device for screening marine microbial consortium, Frontiers in Microbiology, vol.13, 1031439, 2022.12. |
| 26. |
Yusuke Tahara, Fumihiro Sassa, Ryo Takigawa, Yuma Kurihara, Development of a microfluidic-based taste sensor using lipid polymer membrane, Japanese Journal of Applied Physics, 10.35848/1347-4065/acb4fa, 62, 2023.06, This study aims to develop a microfluidic-based taste sensor for detecting time-dependent human taste sensations. Lipid polymer membranes were welded to perforated polycarbonate films with organic solvents to monitor the adsorption and desorption of taste substances to lipid polymer membranes and to physically immobilize lipid polymer membranes to withstand the pressure of a pumped liquid. A polydimethylsiloxane flow channel was bonded chemically to the polycarbonate film with the lipid polymer membrane using 3-aminopropylethoxysilane. A fabricated microfluidic-based taste sensor could measure the membrane potential change with time due to the adsorption and desorption of tannic acid, an astringency substance, onto a lipid polymer membrane. The proposed sensor could be useful as a tool for assessing the time-course changes in human taste.. |
| 27. |
Lingpu Ge, Xiao Ye, Zeping Yu, Bin Chen, Chuanjun Liu, Hao Guo, Shiyi Zhang, Fumihiro Sassa, Kenshi Hayashi, A fully inkjet-printed disposable gas sensor matrix with molecularly imprinted gas-selective materials, npj Flexible Electronics, 10.1038/s41528-022-00168-6, 6, 1, 2022.12, A method was used to fabricate a fully inkjet-printed gas sensor matrix on photographic paper. An electrode matrix comprising 36 interdigital electrodes in a high-density layout that is easy to integrate has been fabricated using a combination of insulating ink and commercial silver ink. Molecular-imprinted polymer (MIP) inks were then made using a simple solution mixing method, and these inks were printed together with carbon black ink on the electrode matrix to complete production of the sensor. Finally, experimental dynamic sensing of volatile organic compounds verifies that for detection of gases corresponding to the MIP template molecules, the MIP layer offers improvements in both sensitivity and selectivity when compared with non-imprinted polymer layers. The matrix can produce a response of more than 20% to 3 ppm propenoic acid gas through adjustment of the printing times for the carbon black layer and the MIP layer.. |
| 28. |
Shiyi Zhang, Joseph Wang, Kenshi Hayashi, Fumihiro Sassa, Monolithic processing of a layered flexible robotic actuator film for kinetic electronics, SCIENTIFIC REPORTS, 10.1038/s41598-021-99500-9, 11, 1, 20015-20015, 2021.10, Low-invasive soft robotic techniques can potentially be used for developing next-generation body-machine interfaces. Most soft robots require complicated fabrication processes involving 3D printing and bonding/assembling. In this letter, we describe a monolithic soft microrobot fabrication process for the mass production of soft film robots with a complex structure by simple 2D processing of a robotic actuator film. The 45 mu g/mm(2) lightweight film robot can be driven at a voltage of CMOS compatible 5 V with 0.15 mm(-1) large curvature changes; it can generate a force 5.7 times greater than its self-weight. In a durability test, actuation could be carried out over 8000 times without degradation. To further demonstrate this technique, three types of film robots with multiple degrees of freedom and a moving illuminator robot were fabricated. This technique can easily integrate various electrical circuits developed in the past to robotic systems and can be used for developing advanced wearable sensing devices; it can be called "Kinetic electronics".. |
| 29. |
Ryosuke Nakai, Hiroyuki Kusada, Fumihiro Sassa, Susumu Morigasaki, Hisayoshi Hayashi, Naoki Takaya, Hideyuki Tamaki, Draft genome sequence of novel filterable rhodospirillales bacterium strain tmpk1, isolated from soil, Microbiology Resource Announcements, 10.1128/MRA.00393-21, 10, 28, e0039321, 2021.07, We report the draft genome sequence of novel Rhodospirillales bacterium strain TMPK1, isolated from a micropore-filtered soil suspension. This strain has a genome of 4,249,070 bp, comprising 4,151 protein-coding sequences. The genome sequence data further suggest that strain TMPK1 is an alphaproteobacterium capable of carotenoid production.. |
| 30. |
Lingpu Ge, Xiao Ye, Bin Chen, Chuanjun Liu, Hao Guo, Fumihiro Sassa, Kenshi Hayashi, Chemiresistor sensor matrix prepared by full-printing processes, Flexible and Printed Electronics, 10.1088/2058-8585/abec19, 6, 1, 015013, 2021.03, Abstract
Herein, we report a novel full printing process for fabricating chemiresistor gas sensor matrixes on photographic paper with an inkjet printer. Sensor matrices, which can increase a number of sensors significantly compared to a serial sensor array, were printed on one piece of A4 photographic paper. Each sensor matrix contains 36 interdigital electrodes in an area of less than 11 mm2, which greatly improves the density of the sensor. The basic architecture of the sensor matrix is electrodes that row and column intersecting. In order to insulate the row and column electrodes from meeting each other, an insulating layer needs to be fabricated at the point of intersection between the row and column electrodes. The insulation layer was produced by adjusting the number of printing passes and shape of the printing pattern of color pigment ink. Carbon black (CB) was used to form a chemosensitive composite by changing its resistivity with a specific polymer for the preparation of sensing material. In order to make the sensing material can be printed, it is necessary to disperse CB first. CB was dispersed in aqueous solution with sodium dodecyl sulfate added as a surfactant to lower the surface tension, which enabled printing of CB using an inkjet printer. Some polymers have certain adsorption characteristics for gases. According to the different gas properties, the adsorption characteristics are also different. By adding polyethylene glycol polymer to the CB layer, the response to four gases with different properties is improved. Compared with the drop coating, the full-printing sensors not only reduces the production time significantly, but also improves the gas response magnitude to ethanol by about three times. The results demonstrate that the developed sensor can be used as a low cost, disposable, and easily printable chemical sensor. . |
| 31. |
Yasuhiro Kusuda, Zhongyuan Yang, Kohei Semasa, Fumihiro Sassa, Kenshi Hayashi, Odor Source Detection with High Speed Multi Gas Sensing Robot System using AuNPs-Fluorescent Molecular coupling Opt-Chemical LSPR Sensor, Proceedings of IEEE Sensors, 10.1109/SENSORS47125.2020.9278605, 2020-October, 2020.10, The Localized Surface Plasmon Resonance (LSPR) gas sensor is a promising for mounting on the robot due to an advantage of high-speed response speed and low power consumption. In addition, it is possible to change the characteristic by coating fluorescent dye on the LSPR surface. In this research, we have developed a robot equipped with multi LSPR gas sensor module for the purpose of the identification of gas species.. |
| 32. |
Lin Chen, Noriko Shiramatsu, Bin Chen, Fumihiro Sassa, Shoichi Sameshima, Tatsuya Seki, Kenshi Hayashi, Ultra-high Sensitive SERS Gas Sensor to detect Geosmin, Proceedings of IEEE Sensors, 10.1109/SENSORS47125.2020.9278909, 2020-October, 2020.10, Geosmin (GSM) with an earthy odor resembling is often accompanied by 2-methylisoborneol (MIB), which caused the earthy and musty taste of drinking water. To detect trace GSM solution, we designed gas sensor by Surface-enhanced Raman Scattering (SERS) technology which has the capacity of single molecule detection. With our ultra-high sensitivity detection system, response range from 10 ppt to 10 ppb geosmin in ultrapure water was confirmed. Additionally, 100 ppt geosmin in tap water was detectable.. |
| 33. |
Kohei Semasa, Fumihiro Sassa, Kenshi Hayashi, 2D LSPR gas sensor with Au/Ag core-shell structure coated by fluorescent dyes, 2020 IEEE SENSORS, 10.1109/SENSORS47125.2020.9278828, 2020-October, 2020.10. |
| 34. |
Fumihiro Sassa, Gokul Chandra Biswas, Hiroaki Suzuki, Microfabricated electrochemical sensing devices, Lab on a Chip, 10.1039/c9lc01112a, 20, 8, 1358-1389, 2020.04, Electrochemistry provides possibilities to realize smart microdevices of the next generation with high functionalities.. |
| 35. |
Zhongyuan Yang, Fumihiro Sassa, Kenshi Hayashi, A Robot Equipped with a High-Speed LSPR Gas Sensor Module for Collecting Spatial Odor Information from On-Ground Invisible Odor Sources, ACS Sensors, 10.1021/acssensors.8b00214, 3, 6, 1174-1181, 2018.06. |
| 36. |
TAKAHIRO WATANABE, FUMIHIRO SASSA, YOSHITAKA YOSHIZUMI, HIROAKI SUZUKI, Review of Microfluidic Devices for On-Chip Chemical Sensing, Electronics and Communications in Japan, 10.1002/ecj.11944, 100, 4, 25-32, 2017.04. |
| 37. |
Sho Shinohara, You Chiyomaru, Fumihiro Sassa, Chuanjun Liu, Kenshi Hayashi, Molecularly imprinted filtering adsorbents for odor sensing, Sensors (Switzerland), 10.3390/s16111974, 16, 11, 1974-1974, 2016.11, Versatile odor sensors that can discriminate among huge numbers of environmental odorants are desired in many fields, including robotics, environmental monitoring, and food production. However, odor sensors comparable to an animal’s nose have not yet been developed. An animal’s olfactory system recognizes odor clusters with specific molecular properties and uses this combinatorial information in odor discrimination. This suggests that measurement and clustering of odor molecular properties (e.g., polarity, size) using an artificial sensor is a promising approach to odor sensing. Here, adsorbents composed of composite materials with molecular recognition properties were developed for odor sensing. The selectivity of the sensor depends on the adsorbent materials, so specific polymeric materials with particular solubility parameters were chosen to adsorb odorants with various properties. The adsorption properties of the adsorbents could be modified by mixing adsorbent materials. Moreover, a novel molecularly imprinted filtering adsorbent (MIFA), composed of an adsorbent substrate covered with a molecularly imprinted polymer (MIP) layer, was developed to improve the odor molecular recognition ability. The combination of the adsorbent and MIP layer provided a higher specificity toward target molecules. The MIFA thus provides a useful technique for the design and control of adsorbents with adsorption properties specific to particular odor molecules.. |
| 38. |
Kazuhiro Ikemoto, Takafumi Seki, Shohei Kimura, Yui Nakaoka, Shinnosuke Tsuchiya, Fumihiro Sassa, Masatoshi Yokokawa, Hiroaki Suzuki, Microfluidic Separation of Redox Reactions for Coulometry Based on Metallization at the Mixed Potential, Analytical Chemistry, 10.1021/acs.analchem.6b01234, 88, 19, 9427-9434, 2016.10. |
| 39. |
Hirotaka Obata, Tomoaki Kuji, Kenichi Kojima, Fumihiro Sassa, Masatoshi Yokokawa, Kazuhiro Takekoshi, Hiroaki Suzuki, Electrochemical Bubble-Based Bidirectional Microfluidic Transport, ACS Sensors, 10.1021/acssensors.5b00059, 1, 2, 190-196, 2016.02. |
| 40. |
Fumihiro Sassa, Yazan Al-Zain, Takahiro Ginoza, Shuichi Miyazaki, Hiroaki Suzuki, Miniaturized shape memory alloy pumps for stepping microfluidic transport, Sensors and Actuators B: Chemical, 10.1016/j.snb.2011.12.085, 165, 1, 157-163, 2012.04. |
| 41. |
Fumihiro Sassa, Hind Laghzali, Junji Fukuda, Hiroaki Suzuki, Coulometric Detection of Components in Liquid Plugs by Microfabricated Flow Channel and Electrode Structures, Analytical Chemistry, 10.1021/ac102289a, 82, 20, 8725-8732, 2010.10. |
| 42. |
Yuki Seto, Rina Inaba, Tomoaki Okuyama, Fumihiro Sassa, Hiroaki Suzuki, Junji Fukuda, Engineering of capillary-like structures in tissue constructs by electrochemical detachment of cells, Biomaterials, 10.1016/j.biomaterials.2009.11.104, 31, 8, 2209-2215, 2010.03. |
| 43. |
Shintaro Takahashi, Hironori Yamazoe, Fumihiro Sassa, Hiroaki Suzuki, Junji Fukuda, Preparation of coculture system with three extracellular matrices using capillary force lithography and layer-by-layer deposition, Journal of Bioscience and Bioengineering, 10.1016/j.jbiosc.2009.06.013, 108, 6, 544-550, 2009.12, Micropatterned cocultures were fabricated with 3 extracellular matrices, hyaluronic acid (HA), fibronectin, and collagen. The feature of the fabrication processes is to avoid the use of potentially cytotoxic materials and utilize capillary force of the solution and interactions between the extracellular matrix components. The coculture system can be used to investigate the effects of heterocellular interactions on cellular fate. Direct heterocellular connections between hepatocytes and fibroblasts were visualized by the transcellular diffusion of fluorescein in this coculture system. The interactions between hepatocytes and fibroblasts were crucial for the maintenance of albumin synthesis by hepatocytes. The coculture system was also beneficial for investigating the effects of cell-cell interactions on the induction of embryonic stem (ES) cell differentiation. In cocultures grown in a sea-island pattern, ES cells formed isolated colonies surrounded by PA6 cells and differentiated into neurons with branched neurites that extended from the colonies. This versatile and biocompatible coculture system could potentially be a powerful tool for investigating cell-cell interaction and for tissue engineering applications. © 2009 The Society for Biotechnology, Japan.. |
| 44. |
Yoshifumi Shimizu, Atsushi Takashima, Wataru Satoh, Fumihiro Sassa, Junji Fukuda, Hiroaki Suzuki, Biochip with integrated pumps for plug-based sequential exchange of solutions, Sensors and Actuators B: Chemical, 10.1016/j.snb.2009.04.048, 140, 2, 649-655, 2009.07. |
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Fumihiro Sassa, Junji Fukuda, Hiroaki Suzuki, Microprocessing of liquid plugs for bio/chemical analyses, Analytical Chemistry, 10.1021/ac800492v, 80, 16, 6206-6213, 2008.08, A microfluidic device and operation to handle liquid plugs for biochemical analyses were developed for efficient handling of plugs of many solutions. A major part of the device was a T-junction consisting of a main flow channel and a handling flow channel. Unit operations including attachment of plugs, division of a plug, sorting of plugs, and formation of plugs of various lengths enabled controlled sequential reactions in a microflow channel. Rapid mixing could easily be achieved by moving a plug formed by merging two plugs back and forth. The device could be used for efficient characterization of performance in bio/chemical sensing. In experiments using L-glutamate oxidase, plugs containing an enzyme or a substrate were formed, mixed sequentially, and the intensity of fluorescence from plugs of different concentrations of L-glutamate or pHs could be measured simultaneously. Cross-contamination of plugs by neighboring plugs poses a problem in using the same flow channel repeatedly. However, the influence could be minimized by using a cleansing plug placed between them in a sufficiently hydrophobic flow channel and by processing the plugs at a low velocity. The device can be a critical component for microprocessing in various bio/chemical analyses. © 2008 American Chemical Society.. |
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Fumihiro Sassa, Katsuya Morimoto, Wataru Satoh, Hiroaki Suzuki, Electrochemical techniques for microfluidic applications, Electrophoresis, 10.1002/elps.200700581, 29, 9, 1787-1800, 2008.05, Eletrochemical principles provide key techniques to promote the construction of bio/chemical microsystems of the next generation. There is a wealth of technology for the microfabrication of bio/chemical sensors. In addition, microfluidic transport in a network of flow channels, pH regulation, and automatic switching can be realized by electro-chemical principles. Since the basic components of the devices are electrode patterns, the integration of different components is easily achieved. With these techniques, bio/chemical assays that require the exchange of solutions can be conducted on a chip. Furthermore, autonomous microanalysis systems that can carry out necessary procedures are beginning to be realized. In this article, techniques developed in our group will be comprehensively introduced. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.. |
